نتایج جستجو برای: RNA-based therapy
تعداد نتایج: 3687214 فیلتر نتایج به سال:
background: recently, the use of t7 rna polymerase instead of other viral and cellular promoters is increasing due to high efficacy of transcription in the cell cytoplasm by this polymerase. in order to translate the transcripts produced by t7 rna polymerase in mammalian cell lines, it is necessary to include internal ribosome entry site (ires) sequences. in addition, if sequence of poly a sign...
Nucleic acids play different roles besides storing information and proteins coding. For example, single-stranded nucleic acids can fold into complicated structures with capability of molecular detection, catalyzing bioreactions and therapy. The development of RNA-based therapies has been rapidly progressed in the recent years. RNA aptamers are biomolecules with a size of 10 to 50 nm that can be...
a 25-year-old female presented to the infertility opd with complaints of secondary infertility and pain lower abdomen with watery discharge for the past five days. she had history of undergoing hysterosalpingography in a private hospital ten days back. the interventions included drainage of pyometra, endometrial biopsy for routine and afb smear/ culture, confirmation of diagnosis by m rna-base...
anxiety is one common disorder during childhood. in curing anxiety disorders, there are different types of psychological remedies, pharmotherapy, family therapy, and music therapy that can improve the individual’s anxiety, but we need some other remedies to improve social and emotional relationship and interactions. considering the importance of curing the anxiety disorders, the effect of sand ...
Background: In gene therapy, the use of RNA molecules as therapeutic agents has shown advantages over plasmid DNA, including higher levels of safety. However, transient nature of RNA has been a major obstacle in application of RNA in gene therapy. Methods: Here, we used the internal ribosomal entry site of encephalomyocarditis virus and the 3’ non-translated region of Poliovirus to design an en...
background: in gene therapy, the use of rna molecules as therapeutic agents has shown advantages over plasmid dna, including higher levels of safety. however, transient nature of rna has been a major obstacle in application of rna in gene therapy. methods: here, we used the internal ribosomal entry site of encephalomyocarditis virus and the 3’ non-translated region of poliovirus to design an en...
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